Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice

Reduced expression of glutamate decarboxylase 67 (GAD67), encoded by the Gad1 gene, is a consistent finding in postmortem brains of patients with several psychiatric disorders, including schizophrenia, bipolar disorder and major depressive disorder. The dysfunction of GAD67 in the brain is implicate...

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Bibliographic Details
Published in:Mol Brain
Main Authors: Miyata, Shigeo, Kakizaki, Toshikazu, Fujihara, Kazuyuki, Obinata, Hideru, Hirano, Touko, Nakai, Junichi, Tanaka, Mika, Itohara, Shigeyoshi, Watanabe, Masahiko, Tanaka, Kenji F., Abe, Manabu, Sakimura, Kenji, Yanagawa, Yuchio
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789591/
https://ncbi.nlm.nih.gov/pubmed/33413507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-020-00713-2
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