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DNA methylation abnormalities of imprinted genes in congenital heart disease: a pilot study

BACKGROUND: Congenital heart disease (CHD) is resulted from the interaction of genetic aberration and environmental factors. Imprinted genes, which are regulated by epigenetic modifications, are essential for the normal embryonic development. However, the role of imprinted genes in the etiology of C...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Med Genomics
Hauptverfasser: Chang, Shaoyan, Wang, Yubo, Xin, Yu, Wang, Shuangxing, Luo, Yi, Wang, Li, Zhang, Hui, Li, Jia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789576/
https://ncbi.nlm.nih.gov/pubmed/33407475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00848-0
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