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Abnormal DNA Methylation of Imprinted Loci in Human Preimplantation Embryos

PURPOSE: To evaluate the epigenetic risk linked to assisted reproductive technology (ART) at single-embryo level by analyzing the methylation status of imprinted H19, PEG1, and KvDMR1 in human preimplantation embryos. METHODS: A total of 254 human day 3 embryos produced by ART procedures were collec...

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Detalhes bibliográficos
Main Authors: Shi, Xiaoyun, Chen, Shiling, Zheng, Haiyan, Wang, Lele, Wu, Yaqin
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126214/
https://ncbi.nlm.nih.gov/pubmed/24406788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719113519173
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