Combined treatment with enteric neural stem cells and chondroitinase ABC reduces spinal cord lesion pathology

BACKGROUND: Spinal cord injury (SCI) presents a significant challenge for the field of neurotherapeutics. Stem cells have shown promise in replenishing the cells lost to the injury process, but the release of axon growth-inhibitory molecules such as chondroitin sulfate proteoglycans (CSPGs) by activ...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Jevans, Benjamin, James, Nicholas D., Burnside, Emily, McCann, Conor J., Thapar, Nikhil, Bradbury, Elizabeth J., Burns, Alan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789480/
https://ncbi.nlm.nih.gov/pubmed/33407795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02031-9
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