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Adapting the randomised controlled trial (RCT) for precision medicine: introducing the nested-precision RCT (npRCT)

Adaptations to the gold standard randomised controlled trial (RCT) have been introduced to decrease trial costs and avoid high sample sizes. To facilitate development of precision medicine algorithms that aim to optimise treatment allocation for individual patients, we propose a new RCT adaptation t...

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Vydáno v:Trials
Hlavní autoři: Kappelmann, Nils, Müller-Myhsok, Bertram, Kopf-Beck, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788903/
https://ncbi.nlm.nih.gov/pubmed/33407710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04965-0
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