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Adapting the randomised controlled trial (RCT) for precision medicine: introducing the nested-precision RCT (npRCT)

Adaptations to the gold standard randomised controlled trial (RCT) have been introduced to decrease trial costs and avoid high sample sizes. To facilitate development of precision medicine algorithms that aim to optimise treatment allocation for individual patients, we propose a new RCT adaptation t...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Kappelmann, Nils, Müller-Myhsok, Bertram, Kopf-Beck, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788903/
https://ncbi.nlm.nih.gov/pubmed/33407710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04965-0
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