Construction and characterization of a novel glucose dehydrogenase-leucine dehydrogenase fusion enzyme for the biosynthesis of l-tert-leucine

BACKGROUND: Biosynthesis of l-tert-leucine (l-tle), a significant pharmaceutical intermediate, by a cofactor regeneration system friendly and efficiently is a worthful goal all the time. The cofactor regeneration system of leucine dehydrogenase (LeuDH) and glucose dehydrogenase (GDH) has showed grea...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Liao, Langxing, Zhang, Yonghui, Wang, Yali, Fu, Yousi, Zhang, Aihui, Qiu, Ruodian, Yang, Shuhao, Fang, Baishan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788806/
https://ncbi.nlm.nih.gov/pubmed/33407464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01501-2
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