Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome

Centrosomes are composed of a centriolar core surrounded by a pericentriolar material (PCM) matrix that docks microtubule-nucleating γ-tubulin complexes. During mitotic entry, the PCM matrix increases in size and nucleating capacity in a process called centrosome maturation. Polo-like kinase 1 (PLK1...

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Gepubliceerd in:J Cell Biol
Hoofdauteurs: Ohta, Midori, Zhao, Zhiling, Wu, Di, Wang, Shaohe, Harrison, Jennifer L., Gómez-Cavazos, J. Sebastián, Desai, Arshad, Oegema, Karen F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788462/
https://ncbi.nlm.nih.gov/pubmed/33399854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202009083
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