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Axin localizes to the centrosome and is involved in microtubule nucleation
Axin is known to have an important role in the degradation of β-catenin in the Wnt pathway. Here, we reveal a new function of Axin at the centrosome. Axin was localized to the centrosome in various cell lines and formed a complex with γ-tubulin. Knockdown of Axin reduced the localization of γ-tubuli...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711835/ https://ncbi.nlm.nih.gov/pubmed/19390532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.45 |
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