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Impaired endoplasmic reticulum-mitochondrial signaling in ataxia-telangiectasia
There is evidence that ATM mutated in ataxia-telangiectasia (A-T) plays a key role in protecting against mitochondrial dysfunction, the mechanism for which remains unresolved. We demonstrate here that ATM-deficient cells are exquisitely sensitive to nutrient deprivation, which can be explained by de...
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| Publicado no: | iScience |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7788243/ https://ncbi.nlm.nih.gov/pubmed/33437944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101972 |
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