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Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance

BACKGROUND & AIMS: Cancer-associated fibroblasts (CAFs) play a key role in the cancer process, but the research progress is hampered by the paucity of preclinical models that are essential for mechanistic dissection of cancer cell–CAF interactions. Here, we aimed to establish 3-dimensional (3D)...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Mol Gastroenterol Hepatol
Main Authors: Liu, Jiaye, Li, Pengfei, Wang, Ling, Li, Meng, Ge, Zhouhong, Noordam, Lisanne, Lieshout, Ruby, Verstegen, Monique M.A., Ma, Buyun, Su, Junhong, Yang, Qin, Zhang, Ruyi, Zhou, Guoying, Carrascosa, Lucia Campos, Sprengers, Dave, IJzermans, Jan N.M., Smits, Ron, Kwekkeboom, Jaap, van der Laan, Luc J.W., Peppelenbosch, Maikel P., Pan, Qiuwei, Cao, Wanlu
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788239/
https://ncbi.nlm.nih.gov/pubmed/32932015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.09.003
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