WLS-Wnt signaling promotes neuroendocrine prostate cancer

Neuroendocrine prostate cancer (NEPC) is a lethal prostate cancer subtype arising as a consequence of more potent androgen receptor (AR) targeting in castration-resistant prostate cancer (CRPC). Its molecular pathogenesis remains elusive. Here, we report that the Wnt secretion mediator Wntless (WLS)...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Bland, Tyler, Wang, Jing, Yin, Lijuan, Pu, Tianjie, Li, Jingjing, Gao, Jin, Lin, Tzu-Ping, Gao, Allen C., Wu, Boyang Jason
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788232/
https://ncbi.nlm.nih.gov/pubmed/33437943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101970
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