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Experimental and bioinformatics considerations in cancer application of single cell genomics
Single cell genomics offers an unprecedented resolution to interrogate genetic heterogeneity in a patient’s tumour at the intercellular level. However, the DNA yield per cell is insufficient for today’s sequencing library preparation protocols. This necessitates DNA amplification which is a key sour...
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| Publicado no: | Comput Struct Biotechnol J |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Research Network of Computational and Structural Biotechnology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7788095/ https://ncbi.nlm.nih.gov/pubmed/33489004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.12.021 |
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