Antisense oligonucleotide and adjuvant exercise therapy reverse fatigue in old mice with myotonic dystrophy

Patients with myotonic dystrophy type 1 (DM1) identify chronic fatigue as the most debilitating symptom, which manifests in part as prolonged recovery after exercise. Clinical features of DM1 result from pathogenic gain-of-function activity of transcripts containing an expanded microsatellite CUG re...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Hu, Ningyan, Kim, Eunjoo, Antoury, Layal, Li, Jia, González-Pérez, Paloma, Rutkove, Seward B., Wheeler, Thurman M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787993/
https://ncbi.nlm.nih.gov/pubmed/33473325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.11.014
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky