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Simultaneous Determination of Ropivacaine and 3-Hydroxy Ropivacaine in Cerebrospinal Fluid by UPLC-MS/MS

In this paper, a UPLC-MS/MS method was developed for the determination of ropivacaine and its metabolite 3-hydroxy ropivacaine in cerebrospinal fluid. The cerebrospinal fluid was processed by ethyl acetate liquid-liquid extraction. The multiple reaction monitoring (MRM) mode was used for quantitativ...

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Détails bibliographiques
Publié dans:Biomed Res Int
Auteurs principaux: Chen, Siyuan, Ma, Jianshe, Wang, Xianqin, Zhou, Quan
Format: Artigo
Langue:Inglês
Publié: Hindawi 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787762/
https://ncbi.nlm.nih.gov/pubmed/33490261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8844866
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