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Short-term enhancement of motor neuron synaptic exocytosis during early aging extends lifespan in Caenorhabditis elegans

Age-related mobility decline is often associated with negative physical and psychological outcomes, such as frailty, in the elderly population. In C. elegans, during the early stage of the aging process, a progressive deficit of synaptic exocytosis in the motor neurons results in a functional declin...

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Bibliographic Details
Published in:Exp Biol Med (Maywood)
Main Authors: Ching, Tsui-Ting, Chen, Yen-Chieh, Li, Guang, Liu, Jianfeng, Xu, X Z Shawn, Hsu, Ao-Lin
Format: Artigo
Language:Inglês
Published: SAGE Publications 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787544/
https://ncbi.nlm.nih.gov/pubmed/32854519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220950639
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