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Critical role of synovial tissue–resident macrophage niche in joint homeostasis and suppression of chronic inflammation

Little is known about the mechanisms regulating the transition of circulating monocytes into pro- or anti-inflammatory macrophages in chronic inflammation. Here, we took advantage of our novel mouse model of rheumatoid arthritis, in which Flip is deleted under the control of a CD11c promoter (HUPO m...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Huang, Qi-Quan, Doyle, Renee, Chen, Shang-Yang, Sheng, Qicong, Misharin, Alexander V., Mao, Qinwen, Winter, Deborah R., Pope, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787490/
https://ncbi.nlm.nih.gov/pubmed/33523968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd0515
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