Locally renewing resident synovial macrophages provide a protective barrier for the joint

Macrophages are considered to contribute to chronic inflammatory diseases such as rheumatoid arthritis(1). However, both the exact origin and the role of macrophages in inflammatory joint disease remain unclear. Here we use fate-mapping approaches in conjunction with three-dimensional light-sheet fl...

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Publicat a:Nature
Autors principals: Culemann, Stephan, Grüneboom, Anika, Nicolás-Ávila, José Ángel, Weidner, Daniela, Lämmle, Katrin Franziska, Rothe, Tobias, Quintana, Juan A., Kirchner, Philipp, Krljanac, Branislav, Eberhardt, Martin, Ferrazzi, Fulvia, Kretzschmar, Elke, Schicht, Martin, Fischer, Kim, Gelse, Kolja, Faas, Maria, Pfeifle, René, Ackermann, Jochen A., Pachowsky, Milena, Renner, Nina, Simon, David, Haseloff, Reiner F., Ekici, Arif B., Bäuerle, Tobias, Blasig, Ingolf E., Vera, Julio, Voehringer, David, Kleyer, Arnd, Paulsen, Friedrich, Schett, Georg, Hidalgo, Andrés, Krönke, Gerhard
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805223/
https://ncbi.nlm.nih.gov/pubmed/31391580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1471-1
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