Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model

Diffuse large B cell lymphomas (DLBCL) are a highly heterogeneous subtype of Non Hodgkin Lymphoma (NHL), accounting for about 25% of NHL. Despite an increased progression-free survival upon therapy, 40–50% of patients develop relapse/refractory disease, therefore there remains an important medical n...

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Udgivet i:PLoS One
Main Authors: Cremasco, Floriana, Menietti, Elena, Speziale, Dario, Sam, Johannes, Sammicheli, Stefano, Richard, Marine, Varol, Ahmet, Klein, Christian, Umana, Pablo, Bacac, Marina, Colombetti, Sara, Perro, Mario
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787458/
https://ncbi.nlm.nih.gov/pubmed/33406104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241091
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