Delivery of hepatocyte growth factor mRNA from nanofibrillar scaffolds in a pig model of peripheral arterial disease

BACKGROUND: Chemical modification of mRNA (mmRNA) substantially improves their stability and translational efficiency within cells. Nanofibrillar collagen scaffolds were previously shown to enable the spatially localized delivery and temporally controlled release of mmRNA encoding HGF both in vitro...

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Опубликовано в: :Regen Med
Главные авторы: S Zaitseva, Tatiana, Yang, Guang, Dionyssiou, Dimitris, Zamani, Maedeh, Sawamura, Steve, Yakubov, Eduard, Ferguson, James, Hallett, Richard L, Fleischmann, Dominik, Paukshto, Michael V, Huang, Ngan F
Формат: Artigo
Язык:Inglês
Опубликовано: Future Medicine Ltd 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787177/
https://ncbi.nlm.nih.gov/pubmed/32772903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/rme-2020-0023
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