Delivery of hepatocyte growth factor mRNA from nanofibrillar scaffolds in a pig model of peripheral arterial disease

BACKGROUND: Chemical modification of mRNA (mmRNA) substantially improves their stability and translational efficiency within cells. Nanofibrillar collagen scaffolds were previously shown to enable the spatially localized delivery and temporally controlled release of mmRNA encoding HGF both in vitro...

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Udgivet i:Regen Med
Main Authors: S Zaitseva, Tatiana, Yang, Guang, Dionyssiou, Dimitris, Zamani, Maedeh, Sawamura, Steve, Yakubov, Eduard, Ferguson, James, Hallett, Richard L, Fleischmann, Dominik, Paukshto, Michael V, Huang, Ngan F
Format: Artigo
Sprog:Inglês
Udgivet: Future Medicine Ltd 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787177/
https://ncbi.nlm.nih.gov/pubmed/32772903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/rme-2020-0023
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