Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells

Leukemia stem cells (LSCs) are believed to have more distinct vulnerabilities than the bulk acute myeloid leukemia (AML) cells, but their rarity and the lack of universal markers for their prospective isolation hamper their study. We report that genetically clonal induced pluripotent stem cells (iPS...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wesely, Josephine, Kotini, Andriana G., Izzo, Franco, Luo, Hanzhi, Yuan, Han, Sun, Jun, Georgomanoli, Maria, Zviran, Asaf, Deslauriers, André G., Dusaj, Neville, Nimer, Stephen D., Leslie, Christina, Landau, Dan A., Kharas, Michael G., Papapetrou, Eirini P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786450/
https://ncbi.nlm.nih.gov/pubmed/32492433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107688
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