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Studying leukemia stem cell properties and vulnerabilities with human iPSCs

The reprogramming of cancer cells into induced pluripotent stem cells (iPSCs) can capture entire cancer genomes, and thus create genetically faithful models of human cancers. By providing stringent genetically clonal conditions, iPSC modeling can also unveil non-genetic sources of cancer heterogenei...

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Publicat a:Stem Cell Res
Autors principals: Spyrou, Nikolaos, Papapetrou, Eirini P.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190184/
https://ncbi.nlm.nih.gov/pubmed/33388708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2020.102117
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