Mild Acid Elution and MHC Immunoaffinity Chromatography Reveal Similar Albeit Not Identical Profiles of the HLA Class I Immunopeptidome

[Image: see text] To understand and treat immunology-related diseases, a comprehensive, unbiased characterization of major histocompatibility complex (MHC) peptide ligands is of key importance. Preceding the analysis by mass spectrometry, MHC class I peptide ligands are typically isolated by MHC imm...

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Bibliographic Details
Published in:J Proteome Res
Main Authors: Sturm, Theo, Sautter, Benedikt, Wörner, Tobias P., Stevanović, Stefan, Rammensee, Hans-Georg, Planz, Oliver, Heck, Albert J. R., Aebersold, Ruedi
Format: Artigo
Language:Inglês
Published: American Chemical Society 2020
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786382/
https://ncbi.nlm.nih.gov/pubmed/33141586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00386
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