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Mechanism of a methylxanthine drug theophylline-induced Ca(2+) signaling and cytotoxicity in AML12 mouse hepatocytes

Theophylline is a methylxanthine drug used in therapy for respiratory diseases. However, the impact of theophylline on Ca(2+) signaling has not been explored in liver cells. This study examined whether theophylline affected Ca(2+) homeostasis and its related cytotoxicity in AML12 mouse hepatocytes....

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Sun, Gwo-Ching, Liang, Wei-Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786170/
https://ncbi.nlm.nih.gov/pubmed/33447363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxres/tfaa084
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