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Iron overload causes oxidative stress and impaired insulin signaling in AML-12 hepatocytes

BACKGROUND: Iron overload is associated with increased severity of nonalcoholic fatty liver disease (NAFLD) including progression to nonalcoholic steatohepatitis and hepatocellular carcinoma. AIMS: To identify potential role(s) of iron in NAFLD, we measured its effects on pathways of oxidative stres...

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Detalhes bibliográficos
Main Authors: Messner, Donald J., Rhieu, Byung Han, Kowdley, Kris V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700657/
https://ncbi.nlm.nih.gov/pubmed/23558563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-013-2648-3
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