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Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron
BACKGROUND: Iron overload is associated with liver toxicity, cirrhosis, and hepatocellular carcinoma in humans. While most iron circulates in blood as transferrin-bound iron, non-transferrin-bound iron (NTBI) also becomes elevated and contributes to toxicity in the setting of iron overload. The mech...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275280/ https://ncbi.nlm.nih.gov/pubmed/18254965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-8-2 |
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