Modeling MyD88 Deficiency In Vitro Provides New Insights in Its Function

Inherited defects in MyD88 and IRAK4, two regulators in Toll-like receptor (TLR) signaling, are clinically highly relevant, but still incompletely understood. MyD88- and IRAK4-deficient patients are exceedingly susceptible to a narrow spectrum of pathogens, with ∼50% lethality in the first years of...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Craig-Mueller, Nils, Hammad, Ruba, Elling, Roland, Alzubi, Jamal, Timm, Barbara, Kolter, Julia, Knelangen, Nele, Bednarski, Christien, Gläser, Birgitta, Ammann, Sandra, Ivics, Zoltán, Fischer, Judith, Speckmann, Carsten, Schwarz, Klaus, Lachmann, Nico, Ehl, Stephan, Moritz, Thomas, Henneke, Philipp, Cathomen, Toni
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786022/
https://ncbi.nlm.nih.gov/pubmed/33424861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.608802
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars