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N-methyl-D-aspartate receptor Activation, Novel Mechanism of Homocysteine Induced Blood Retinal Barrier Dysfunction

BACKGROUND: Elevated levels of amino acid homocysteine (Hcy) recognized as hyperhomocysteinemia (HHcy) was reported in several human visual disorders, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the blood-retinal barrier (BRB) is concomitant with vision...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Tawfik, Amany, Mohamed, Riyaz, Kira, Dina, Alhusban, Suhib, Al-Shabrawey, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785674/
https://ncbi.nlm.nih.gov/pubmed/33159240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-02000-y
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