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TCDD Attenuates EAE Through Induction of FasL on B Cells and Inhibition of IgG Production

Previously we demonstrated that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppressed experimental autoimmune encephalomyelitis (EAE), a model to study multiple sclerosis (MS), through induction of regulatory T cells (Tregs) and suppression of effector T cell function in the spleen. Since B cells an...

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Détails bibliographiques
Publié dans:Toxicology
Auteurs principaux: Kummari, Evangel, Rushing, Erin, Nicaise, Ashleigh, McDonald, Amye, Kaplan, Barbara L. F.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785643/
https://ncbi.nlm.nih.gov/pubmed/33253778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2020.152646
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