Chronic Tear Deficiency Sensitizes Transient Receptor Potential Vanilloid 1-Mediated Responses in Corneal Sensory Nerves

Chronic tear deficiency enhances the excitability of corneal cold-sensitive nerves that detect ocular dryness, which can lead to discomfort in patients with dry eye disease (DED). However, changes in corneal nerve excitations through the polymodal nociceptor “transient receptor potential vanilloid 1...

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Udgivet i:Front Cell Neurosci
Main Authors: Masuoka, Takayoshi, Yamashita, Yuka, Nakano, Katsuya, Takechi, Kenshi, Niimura, Takahiro, Tawa, Masashi, He, Qiang, Ishizawa, Keisuke, Ishibashi, Takaharu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cellular Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785588/
https://ncbi.nlm.nih.gov/pubmed/33424555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.598678
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