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Sensitization of glutamate receptor‐mediated pain behaviour via nerve growth factor‐dependent phosphorylation of transient receptor potential V1 under inflammatory conditions

BACKGROUND AND PURPOSE: Glutamate and metabotropic glutamate (mGlu) receptors on primary sensory neurons are crucial in modulating pain sensitivity. However, it is unclear how inflammation affects mGlu receptor‐mediated nociceptive responses. We therefore investigated the effects of mGlu(1/5) recept...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Br J Pharmacol
Päätekijät: Masuoka, Takayoshi, Yamashita, Yuka, Yoshida, Junko, Nakano, Katsuya, Tawa, Masashi, Nishio, Matomo, Ishibashi, Takaharu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443478/
https://ncbi.nlm.nih.gov/pubmed/32579702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15176
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