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Sensitization of glutamate receptor‐mediated pain behaviour via nerve growth factor‐dependent phosphorylation of transient receptor potential V1 under inflammatory conditions

BACKGROUND AND PURPOSE: Glutamate and metabotropic glutamate (mGlu) receptors on primary sensory neurons are crucial in modulating pain sensitivity. However, it is unclear how inflammation affects mGlu receptor‐mediated nociceptive responses. We therefore investigated the effects of mGlu(1/5) recept...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Masuoka, Takayoshi, Yamashita, Yuka, Yoshida, Junko, Nakano, Katsuya, Tawa, Masashi, Nishio, Matomo, Ishibashi, Takaharu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443478/
https://ncbi.nlm.nih.gov/pubmed/32579702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15176
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