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Sensitization of glutamate receptor‐mediated pain behaviour via nerve growth factor‐dependent phosphorylation of transient receptor potential V1 under inflammatory conditions

BACKGROUND AND PURPOSE: Glutamate and metabotropic glutamate (mGlu) receptors on primary sensory neurons are crucial in modulating pain sensitivity. However, it is unclear how inflammation affects mGlu receptor‐mediated nociceptive responses. We therefore investigated the effects of mGlu(1/5) recept...

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Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Masuoka, Takayoshi, Yamashita, Yuka, Yoshida, Junko, Nakano, Katsuya, Tawa, Masashi, Nishio, Matomo, Ishibashi, Takaharu
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443478/
https://ncbi.nlm.nih.gov/pubmed/32579702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15176
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