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Biased Influences of Low Tumor Purity on Mutation Detection in Cancer
The non-cancerous components in tumor tissues, e.g., infiltrating stromal cells and immune cells, dilute tumor purity and might confound genomic mutation profile analyses and the identification of pathological biomarkers. It is necessary to systematically evaluate the influence of tumor purity. Here...
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| Publicado no: | Front Mol Biosci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785586/ https://ncbi.nlm.nih.gov/pubmed/33425983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.533196 |
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