Minocycline Alleviates Cluster Formation of Activated Microglia and Age-dependent Dopaminergic Cell Death in the Substantia Nigra of Zitter Mutant Rat

Microglial activation is a component of neurodegenerative pathology. Here, we examine whether activated microglia participate in age-related dopaminergic (DA) cell death in the substantia nigra pars compacta (SNc) of the zitter (zi/zi) rat, a mutant characterized by deletion of the attractin gene. C...

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Udgivet i:Acta Histochem Cytochem
Main Authors: Taguchi, Daisuke, Ehara, Ayuka, Kadowaki, Taro, Sakakibara, Shin-ichi, Nakadate, Kazuhiko, Hirata, Koichi, Ueda, Shuichi
Format: Artigo
Sprog:Inglês
Udgivet: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2020
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785462/
https://ncbi.nlm.nih.gov/pubmed/33437100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/ahc.20-00022
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