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Pitx3 is required for development of substantia nigra dopaminergic neurons

Dopaminergic (DA) neurons of substantia nigra in the midbrain control voluntary movement, and their degeneration is the cause of Parkinson's disease. The complete set of genes required to specifically determine the development of midbrain DA subgroups is not known yet. We report here that mice...

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Autors principals: Nunes, Irene, Tovmasian, Lucy T., Silva, Robert M., Burke, Robert E., Goff, Stephen P.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153078/
https://ncbi.nlm.nih.gov/pubmed/12655058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0230529100
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