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Functional Water Wires Catalyze Long-Range Proton Pumping in the Mammalian Respiratory Complex I

[Image: see text] The respiratory complex I is a gigantic (1 MDa) redox-driven proton pump that reduces the ubiquinone pool and generates proton motive force to power ATP synthesis in mitochondria. Despite resolved molecular structures and biochemical characterization of the enzyme from multiple org...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Röpke, Michael, Saura, Patricia, Riepl, Daniel, Pöverlein, Maximilian C., Kaila, Ville R. I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2020
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785131/
https://ncbi.nlm.nih.gov/pubmed/33325238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09209
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