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Functional Water Wires Catalyze Long-Range Proton Pumping in the Mammalian Respiratory Complex I
[Image: see text] The respiratory complex I is a gigantic (1 MDa) redox-driven proton pump that reduces the ubiquinone pool and generates proton motive force to power ATP synthesis in mitochondria. Despite resolved molecular structures and biochemical characterization of the enzyme from multiple org...
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| Pubblicato in: | J Am Chem Soc |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2020
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785131/ https://ncbi.nlm.nih.gov/pubmed/33325238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09209 |
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