Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma.

Precursor states of Multiple Myeloma (MM) and its native tumor microenvironment need in-depth molecular characterization to better stratify and treat patients at risk. Using single-cell RNA sequencing of bone marrow cells from precursor stages, MGUS and smoldering myeloma (SMM), to full-blown MM alo...

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Publicado no:Nat Cancer
Main Authors: Zavidij, Oksana, Haradhvala, Nicholas J., Mouhieddine, Tarek H., Sklavenitis-Pistofidis, Romanos, Cai, Songjie, Reidy, Mairead, Rahmat, Mahshid, Flaifel, Abdallah, Ferland, Benjamin, Su, Nang K., Agius, Michael P., Park, Jihye, Manier, Salomon, Bustoros, Mark, Huynh, Daisy, Capelletti, Marzia, Berrios, Brianna, Liu, Chia-Jen, He, Meng Xiao, Braggio, Esteban, Fonseca, Rafael, Maruvka, Yosef, Guerriero, Jennifer L., Goldman, Melissa, van Allen, Eliezer, McCarroll, Steven A., Azzi, Jamil, Getz, Gad, Ghobrial, Irene M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785110/
https://ncbi.nlm.nih.gov/pubmed/33409501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-020-0053-3
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