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Disome-seq reveals widespread ribosome collisions that promote cotranslational protein folding

BACKGROUND: The folding of proteins is challenging in the highly crowded and sticky environment of a cell. Regulation of translation elongation may play a crucial role in ensuring the correct folding of proteins. Much of our knowledge regarding translation elongation comes from the sequencing of mRN...

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Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Zhao, Taolan, Chen, Yan-Ming, Li, Yu, Wang, Jia, Chen, Siyu, Gao, Ning, Qian, Wenfeng
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784341/
https://ncbi.nlm.nih.gov/pubmed/33402206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02256-0
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