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Kinetic Analysis of Ribosome-bound Fluorescent Proteins Reveals an Early, Stable, Cotranslational Folding Intermediate

Protein folding in cells reflects a delicate interplay between biophysical properties of the nascent polypeptide, the vectorial nature and rate of translation, molecular crowding, and cellular biosynthetic machinery. To better understand how this complex environment affects de novo folding pathways...

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Detalhes bibliográficos
Main Authors: Kelkar, Devaki A., Khushoo, Amardeep, Yang, Zhongying, Skach, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268416/
https://ncbi.nlm.nih.gov/pubmed/22128180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318766
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