Tannic acid suppresses SARS-CoV-2 as a dual inhibitor of the viral main protease and the cellular TMPRSS2 protease

The cell surface protein TMPRSS2 (transmembrane protease serine 2) is an androgen-responsive serine protease important for prostate cancer progression and therefore an attractive therapeutic target. Besides its role in tumor biology, TMPRSS2 is also a key player in cellular entry by the SARS-CoV vir...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Wang, Shao-Chun, Chen, Yeh, Wang, Yu-Chuan, Wang, Wei-Jan, Yang, Chia-Shin, Tsai, Chia-Ling, Hou, Mei-Hui, Chen, Hsiao-Fan, Shen, Yi-Chun, Hung, Mien-Chie
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783773/
https://ncbi.nlm.nih.gov/pubmed/33415017
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