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The impact of post-alignment processing procedures on whole-exome sequencing data
The use of post-alignment procedures has been suggested to prevent the identification of false-positives in massive DNA sequencing data. Insertions and deletions are most likely to be misinterpreted by variant calling algorithms. Using known genetic variants as references for post-processing pipelin...
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| Publié dans: | Genet Mol Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Sociedade Brasileira de Genética
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7783507/ https://ncbi.nlm.nih.gov/pubmed/33306778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2020-0047 |
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