Inhibition of calcium-calmodulin-dependent phosphodiesterase (PDE1) suppresses inflammatory responses

A novel, potent, and highly specific inhibitor of calcium-calmodulin-dependent phosphodiesterases (PDE) of the PDE1 family, ITI-214, was used to investigate the role of PDE1 in inflammatory responses. ITI-214 dose-dependently suppressed lipopolysaccharide (LPS)-induced gene expression of pro-inflamm...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cell Neurosci
Asıl Yazarlar: O'Brien, Jennifer J., O'Callaghan, James P., Miller, Diane B., Chalgeri, Suman, Wennogle, Lawrence P., Davis, Robert E., Snyder, Gretchen L., Hendrick, Joseph P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783477/
https://ncbi.nlm.nih.gov/pubmed/31770590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2019.103449
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller