Nme1 and Nme2 genes exert metastasis-suppressor activities in a genetically engineered mouse model of UV-induced melanoma

NME1 is a metastasis-suppressor gene (MSG), capable of suppressing metastatic activity in cell lines of melanoma, breast carcinoma and other cancer origins without affecting their growth in culture or as primary tumours. Herein, we selectively ablated the tandemly arranged Nme1 and Nme2 genes to ass...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Cancer
Hauptverfasser: Pamidimukkala, Nidhi, Puts, Gemma S., Kathryn Leonard, M., Snyder, Devin, Dabernat, Sandrine, De Fabo, Edward C., Noonan, Frances P., Slominski, Andrzej, Merlino, Glenn, Kaetzel, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Brief Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782836/
https://ncbi.nlm.nih.gov/pubmed/33024267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01096-w
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