Nme1 and Nme2 genes exert metastasis-suppressor activities in a genetically engineered mouse model of UV-induced melanoma

NME1 is a metastasis-suppressor gene (MSG), capable of suppressing metastatic activity in cell lines of melanoma, breast carcinoma and other cancer origins without affecting their growth in culture or as primary tumours. Herein, we selectively ablated the tandemly arranged Nme1 and Nme2 genes to ass...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Pamidimukkala, Nidhi, Puts, Gemma S., Kathryn Leonard, M., Snyder, Devin, Dabernat, Sandrine, De Fabo, Edward C., Noonan, Frances P., Slominski, Andrzej, Merlino, Glenn, Kaetzel, David M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Brief Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782836/
https://ncbi.nlm.nih.gov/pubmed/33024267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01096-w
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