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TRAIL receptor-induced features of epithelial-to-mesenchymal transition increase tumour phenotypic heterogeneity: potential cell survival mechanisms

The continuing efforts to exploit the death receptor agonists, such as the tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), for cancer therapy, have largely been impaired by the anti-apoptotic and pro-survival signalling pathways leading to drug resistance. Cell migration, inv...

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Publicat a:Br J Cancer
Autors principals: Peyre, Ludovic, Meyer, Mickael, Hofman, Paul, Roux, Jérémie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782794/
https://ncbi.nlm.nih.gov/pubmed/33257838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01177-w
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