RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer

BACKGROUND: Oestrogen Receptor 1 (ESR1) mutations are frequently acquired in oestrogen receptor (ER)-positive metastatic breast cancer (MBC) patients who were treated with aromatase inhibitors (AI) in the metastatic setting. Acquired ESR1 mutations are associated with poor prognosis and there is a l...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Dustin, Derek, Gu, Guowei, Beyer, Amanda R., Herzog, Sarah K., Edwards, David G., Lin, Hangqing, Gonzalez, Thomas L., Grimm, Sandra L., Coarfa, Cristian, Chan, Doug W., Kim, Beom-Jun, De La O, Jean-Paul, Ellis, Matthew J., Liu, Dan, Li, Shunqiang, Welm, Alana L., Fuqua, Suzanne A. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782501/
https://ncbi.nlm.nih.gov/pubmed/33257837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01174-z
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