Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition

Glucose metabolism and innate immunity evolved side-by-side. It is unclear if and how the two systems interact with each other during hepatitis B virus (HBV) infections and, if so, which mechanisms are involved. Here, we report that HBV activates glycolysis to impede retinoic acid-inducible gene I (...

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Udgivet i:Nat Commun
Main Authors: Zhou, Li, He, Rui, Fang, Peining, Li, Mengqi, Yu, Haisheng, Wang, Qiming, Yu, Yi, Wang, Fubing, Zhang, Yi, Chen, Aidong, Peng, Nanfang, Lin, Yong, Zhang, Rui, Trilling, Mirko, Broering, Ruth, Lu, Mengji, Zhu, Ying, Liu, Shi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782485/
https://ncbi.nlm.nih.gov/pubmed/33397935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20316-8
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