A carregar...
Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity
The absence of fucose on asparagine-297 of the human immunoglobulin G (IgG) heavy chain has been shown to enhance antibody-dependent cellular cytotoxicity (ADCC) activity by 10- to 100-fold compared to fucosylated antibody. Our lab is studying the use of adeno-associated virus (AAV) as a vector for...
Na minha lista:
| Publicado no: | Mol Ther Methods Clin Dev |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7782200/ https://ncbi.nlm.nih.gov/pubmed/33426147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.11.001 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|