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Anticancer active trifluoromethylated fused triazinones are safe for early-life stages of zebrafish (Danio rerio) and reveal a proapoptotic action

The main purpose of this investigation was to evaluate the effect of anticancer active compounds (I–VIII) on zebrafish development in order to select the safest molecules. Larval mortality, embryo hatchability and malformations were end-points used to assess the acute toxicity among embryos and larv...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Sztanke, Małgorzata, Rzymowska, Jolanta, Sztanke, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782186/
https://ncbi.nlm.nih.gov/pubmed/33390035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1865944
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