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Anticancer active trifluoromethylated fused triazinones are safe for early-life stages of zebrafish (Danio rerio) and reveal a proapoptotic action

The main purpose of this investigation was to evaluate the effect of anticancer active compounds (I–VIII) on zebrafish development in order to select the safest molecules. Larval mortality, embryo hatchability and malformations were end-points used to assess the acute toxicity among embryos and larv...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Sztanke, Małgorzata, Rzymowska, Jolanta, Sztanke, Krzysztof
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782186/
https://ncbi.nlm.nih.gov/pubmed/33390035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1865944
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